So far there has been a total war game for every romanticized age in history, from e.i: Antiquity, Medieval, Colonial, ...etc leading up to the Napoleonic Wars; all except for the Old West. The infamous 'Cowboys & Indians', circa (1865—1895) maybe even from the 1830s.
Imagine the possibilities. The Great Plains Indian tribes could have so many factions such as: Apache, Arapaho, Cherokee, Cheyenne, Comanche Navajo, Paiute, Shoshone, Sioux, Ute, ...etc. Then of course the USA and Mexico factions and possibly the Republic of Texas.
Then there is the amount of possible fun campaigns:
• 'Texas Revolution' and 'Texas Indian Wars' where Texans had to gain independence from Mexico, then with the Texas Rangers defeat the Comanches that devastated Texas settlements, eventually fighting a campaign against the Cheyenne.
• 'Mexican–American War', the Conquest of California, Mexican invasions of Texas throughout, and suppression of a revolt in New Mexico, and a campaign through Mexico to eventually capture Mexico City.
• 'Mormon Wars' where Mormons fought wars in Missouri and Indiana, got expelled, then traveled to Utah and waged war on the US government, and the 'Ute Wars'.
• 'Apache Wars' as they attack Mexico and the US Army with Geronimo.
• 'Sioux Wars' with Sitting Bull, Red Cloud, and Crazy Horse as the Lakota fight valiantly against US westward expansion. Historically after the cruel setbacks of the First Sioux War and Dakota War of 1862, the Arapaho, Cheyenne, and Sioux repelled the US Army in a series of Wars, e.i: Colorado War, Powder River War, Red Cloud's War, barbarous Indian raiding of US forts & settlements in the 1870s, then the final Great Sioux War of 1876 with humiliating defeats of the US Army, most notably the Battle of Little Bighorn, until the Indians were eventually starved out and the Lakota made their last stand at Wolf Mountain.